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TBTU (O-(Benzotriazol-1-yl)-N,N,N’,N’-Tetramethyluronium Tetrafluoroborate)

TBTU is a coupling reagent used for solid-phase peptide synthesis. The compound has been used to study ten different phosphonium and uronium salt-based coupling reagents, which are used to synthesize four peptides. TBTU has been documented as a coupling reagent to synthesize a tetrahydrocarbazole substituted dipeptide in a multi-gram solid-phase synthesis. The compound has also been incorporated with HOBt (hydroxybenzotriazole dihydrate) as a carboxyl activator before the coupling of a C-terminal amino acid with a success rate of 100% coupling.

Product Details

Category Peptide Reagents, Resins & Linkers
Price POA
CAS Number 125700-67-6
Formula C11H16N5O · BF4
Molecular Weight 321.08
Purity 97.0%
Appearance solid crystalline
Availability In Stock
Storage Conditions Room temperature

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