TBTU (O-(Benzotriazol-1-yl)-N,N,N‘,N‘-Tetramethyluronium Tetrafluoroborate)
TBTU is a coupling reagent used for solid-phase peptide synthesis. The compound has been used to study ten different phosphonium and uronium salt-based coupling reagents, which are used to synthesize four peptides. TBTU has been documented as a coupling reagent to synthesize a tetrahydrocarbazole substituted dipeptide in a multi-gram solid-phase synthesis. The compound has also been incorporated with HOBt (hydroxybenzotriazole dihydrate) as a carboxyl activator before the coupling of a C-terminal amino acid with a success rate of 100% coupling.
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Product Details
| Category |
Peptide Reagents, Resins & Linkers |
|---|---|
| Price | Enquire |
| CAS Number | 125700-67-6 |
| Formula | C11H16N5O · BF4 |
| Molecular Weight | 321.08 |
| Purity | 97.0% |
| Appearance | solid crystalline |
| Availability | In Stock |
| Storage Conditions | Room temperature |
| MSDS Data Sheet | Click to download |
| MDL Number | MFCD00077413 |
| Harmonised Tariff | 2933998090 |
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