Py-Bop® also known under the systematic name, benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, is a peptide coupling reagent used in solid phase peptide synthesis. Analogue of the BOP coupling reagent which does not form carcinogenic HMPA as by-product.
It is a reagent for some of the following procedures : synthesis of single labeled oligonucleotides that fluoresce upon matched hybridization, generation of endocrine disruptor chemical binders, Cycloaddition to template-assembled multivalent peptide conjugates.
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