Nitrocefin
Nitrocefin is a chromogenic cephalosporin substrate, developed by Glaxo Research Limited coded 87/312; 3-(2,4 dinitrostyrl) – 6R, 7R) -7-(2 thienylacetamido)-ceph-3-em-4 carboxylic acid, E-isomer. This compound exhibits a rapid distinctive colour change from yellow to red as the amide bond in the beta- lactam ring is hydrolysed by a beta-lactamase (E.C.3.5.2.6.).It is often used as as an indentification stick. It is sensitive to hydrolysis by all known lactamases produced by Gram-positive and Gram-negative bacteria. It is used to detect the presence of beta-lactamase enzymes produced by various microbes.
In Microbiology Nitrocefin is used as a disk for rapid detection of beta-lactamase production in Haemophilus spp., N. gonorrhoeae, M. catarrhalis, staphylococci, enterococci, and anaerobes.
Product Details
| Category |
Antibiotics & Antibacterials Microbiology Products Specialities |
|---|---|
| Price | Enquire |
| CAS Number | 41906-86-9 |
| Formula | C21H16N4O8S2 |
| Molecular Weight | 516.51 |
| Purity | 95.0% |
| Appearance | yellow to orange solid |
| Availability | Enquire |
| Storage Conditions | -18°C |
| MSDS Data Sheet | Click to download |
| MDL Number | Request if not shown |
| Harmonised Tariff | 29349990 |
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