4-(Chloromethyl)Pyridine Hydrochloride
It finds its application as a reagent for protection of carboxyl termini of peptides as 4-picolyl esters, providing a polar ‚handle‘ which aids in separation and purification of the peptide. The group can be introduced in the presence of a base, e.g. tetramethylguanidine, is stable to acid-catalyzed removal of Cbz protecting group and can be removed by base, Na in liquid ammonia or catalytic hydrogenolysis.
Product Details
| Category |
Heterocycles & Building Blocks |
|---|---|
| Price | POA |
| CAS Number | 1822-51-1 |
| Formula | C6H6ClN · HCl |
| Molecular Weight | 164.03 |
| Purity | 97.0% |
| Appearance | cream or pale yellow or pale brown powder |
| Availability | In Stock |
| Storage Conditions | Room temperature |
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