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4-(Chloromethyl)Pyridine Hydrochloride

It finds its application as a reagent for protection of carboxyl termini of peptides as 4-picolyl esters, providing a polar ‘handle’ which aids in separation and purification of the peptide. The group can be introduced in the presence of a base, e.g. tetramethylguanidine, is stable to acid-catalyzed removal of Cbz protecting group and can be removed by base, Na in liquid ammonia or catalytic hydrogenolysis.

Product Details

Category Heterocycles & Building Blocks
Price POA
CAS Number 1822-51-1
Formula C6H6ClN · HCl
Molecular Weight 164.03
Purity 97.0%
Appearance cream or pale yellow or pale brown powder
Availability In Stock
Storage Conditions Room temperature

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