2′,3′-Dideoxycytidine
2′,3′-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. It is also is used as a DNA chain-terminating nucleotide for DNA sequencing methods based on the Sanger chain-termination method.
Product Details
| Category |
Cancer Research and Antivirals Carbohydrates and Nucleosides |
|---|---|
| Price | POA |
| CAS Number | 7481-89-2 |
| Formula | C9H13N3O3 |
| Molecular Weight | 211.22 |
| Purity | 98.0% |
| Appearance | crystalline solid |
| Availability | In Stock |
| Storage Conditions | -18°C |
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