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2′,3′-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. It is also is used as a DNA chain-terminating nucleotide for DNA sequencing methods based on the Sanger chain-termination method.

Product Details

Category Cancer Research and Antivirals
Carbohydrates and Nucleosides
Price POA
CAS Number 7481-89-2
Formula C9H13N3O3
Molecular Weight 211.22
Purity 98.0%
Appearance crystalline solid
Availability In Stock
Storage Conditions -18°C

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