Ophiobolin A (Cochliobolin A)
Ophiobolin A is a fungal metabolite, toxic to many crops and found to have antimicrobial and anticancer activity. Ophiobolin A is a calmodulin antagonist and inhibitor of big conductance Ca2+-activated K+ channel (BKCa) activity. Its anticancer activity may involve inhibition of multiple oncogenic signaling pathways including PI3K/mTOR, Ras/Raf/ERK and CDK/RB. One study suggested the possibility of pyrrolylation of lysine residues on its intracellular target protein(s) as a mechanism of action on various targets.
Product Details
| Category |
API's & Drug Standards Cancer Research and Antivirals |
|---|---|
| Price | Custom packed. Request price on line. |
| CAS Number | 4611-05-6 |
| Formula | C25H36O4 |
| Molecular Weight | 400.6 |
| Purity | 99.0% |
| Appearance | white powder |
| Availability | In Stock |
| Storage Conditions | -18°C |
| MDL Number | Request if not shown |
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