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Ophiobolin A (Cochliobolin A)

Ophiobolin A is a fungal metabolite, toxic to many crops and found to have antimicrobial and anticancer activity. Ophiobolin A is a calmodulin antagonist and inhibitor of big conductance Ca2+-activated K+ channel (BKCa) activity. Its anticancer activity may involve inhibition of multiple oncogenic signaling pathways including PI3K/mTOR, Ras/Raf/ERK and CDK/RB. One study suggested the possibility of pyrrolylation of lysine residues on its intracellular target protein(s) as a mechanism of action on various targets.

Product Details

Category API's & Drug Standards
Cancer Research and Antivirals
Price Custom packed. Request price on line.
CAS Number 4611-05-6
Formula C25H36O4
Molecular Weight 400.6
Purity 99.0%
Appearance white powder
Availability In Stock
Storage Conditions -18°C
MDL Number Request if not shown

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