Tunicamycin from Streptomyces sp.
Antibacterial and antifungal. Blocks the formation of protein N-glycosidic linkages by inhibiting the transfer of N-acetylglucosamine 1-phosphate to dolichol monophosphate. Inhibits bacterial and eukaryote N-acetylglucosamine transferases and prevents formation of N-acetylglucosamine lipid intermediates.
Antibiotics & Antibacterials
|Formula||C38H62N4O16 (Tun B)|
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