FK-506 is a potent, clinically-useful immunosuppressant in the same molecular class as cyclosporin A and rapamycin. Its mechanism of action involves the formation of a high affinity complex (Ki = 0.2 nM) with FK-506 Binding Protein 12 (FKBP12). This complex then inhibits the activity of the calcium/calmodulin-dependent protein phosphatase, calcineurin, leading to disruption of T-cell activation.
API's & Drug Standards
Biochemicals & Diagnostics
Pharma Compounds & Neutraceuticals
|Price||Custom packed. Request price on line.|
|MDL Number||Request if not shown|
Send us your enquiry for Tacrolimus (FK-506). We offer custom pack sizes at special prices. We aim to respond to your enquiry within 24 hours.
We value your input so if you have suggestions regarding new applications for Tacrolimus (FK-506) email us and we will include your contribution on the website.