Tacrolimus (FK-506)
FK-506 is a potent, clinically-useful immunosuppressant in the same molecular class as cyclosporin A and rapamycin. Its mechanism of action involves the formation of a high affinity complex (Ki = 0.2 nM) with FK-506 Binding Protein 12 (FKBP12). This complex then inhibits the activity of the calcium/calmodulin-dependent protein phosphatase, calcineurin, leading to disruption of T-cell activation.
Product Details
| Category |
API's & Drug Standards Biochemicals & Diagnostics Pharma Compounds & Neutraceuticals |
|---|---|
| Price | Custom packed. Request price on line. |
| CAS Number | 104987-11-3 |
| Formula | C44H69NO12 |
| Molecular Weight | 804.0 |
| Purity | Min 99.0% |
| Appearance | White powder |
| Availability | In Stock |
| Storage Conditions | -18°C |
| MDL Number | Request if not shown |
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