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Sorafenib Free Base

Sorafenib is a synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical component of the RAF/MEK/ERK signalling pathway that controls cell division and proliferation; in addition, Sorafenib inhibits the VEGFR-2/PDGFR-beta signalling cascade, thereby blocking tumour angiogenesis. Sorafenib was approved in 2005 for use in the treatment of advanced renal cancer.

Product Details

Category Cancer Research and Antivirals
Price POA
CAS Number 284461-73-0
Formula C21H16ClF3N4O3
Molecular Weight 464.82
Purity 99.0%
Appearance white solid powder
Availability In Stock
Storage Conditions -18ºC

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