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Simvastatin Ammonium Salt

Simvastatin Hydroxy Acid, is a potent reversible inhibitor of HMGCR (HMG-CoA reductase). This simvastatin metabolite reduces cholesterol synthesis and increases low-density lipoprotein (LDL) receptors on cell membranes of liver and extra hepatic tissues. Studies suggest that simvastatin hydroxy acid can be determined in plasma using liquid chromatography–UV detection (LC–UV) or gas chromatography–mass spectrometry (GC–MS). Further studies have shown that the cytochromes CYP3A4, CYP3A5, and CYP2C8 all catalyz the formation of simvastatin hydroxy acid.

Product Details

Category API's & Drug Standards
Diabetes Research
Price POA
CAS Number 139893-43-9
Formula C25H40O6 NH3
Molecular Weight 453.61
Purity 98.0%
Appearance white powder
Availability In Stock
Storage Conditions -18°C

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