Rebeccamycin
Rebeccamycin is a weak topoisomerase I inhibitor isolated from Streptomyces sp. It is structurally similar to staurosporine, but does not show any inhibitory activity against protein kinases. It shows significant antitumor properties in vitro (IC50=480nM against mouse B16 melanoma cells and IC50=500nM against P388 leukemia cells).
Product Details
Category |
Antibiotics & Antibacterials |
---|---|
Price | POA |
CAS Number | 93908-02-2 |
Formula | C27H21Cl2N3O7 |
Molecular Weight | 570.38 |
Purity | 98.0% |
Appearance | solid form |
Availability | In Stock |
Storage Conditions | -18°C |
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