Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. When taken, it is converted to the active metabolite cycloguanil. Proguanil is effective against sporozoites. Proguanil hydrochloride is marketed as Paludrine by AstraZeneca. It has been used for malarial prophylaxis in children with sickle cell disease living in malaria-endemic areas for many years.
API's & Drug Standards
|Formula||C11H15Cl2N5 · HCl|
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