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TSTU (2-Succinimido-1,1,3,3-Tetramethyluronium Tetrafluoroborate)

2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate (TSTU) acts as an efficient coupling agent through rapid activation of carboxylic acids to form N-succinimidyl active esters, which react with primary amines to form carboxamides. It is effective even in the presence of water. TSTU is selective towards amines in the presence of alcoholic group. It is employed as a coupling regent in the synthesis of peptides. With amine-protected alpha-amino acids, it brings about coupling without significant epimerization. It is useful for linking of sensor molecules with amino groups to amino-functionalized AFM (atomic force microscope) tips.

Product Details

Category Peptide Reagents, Resins & Linkers
Price POA
CAS Number 105832-38-0
Formula C9H16BF4N3O3
Molecular Weight 301.05
Appearance white to off white solid
Purity 98.0%
Storage Conditions +4°C

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