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Nitroxoline  (8-Hydroxy-5-nitroquinoline) is an antibiotic that has been in use in Europe for about fifty years. Nitroxoline was shown to cause a decrease in the biofilm density of P. aeruginosa infections, which would allow access to the infection by the immune system in vivo. 8-Hydroxy-5-nitroquinoline is an effective anti-microbial and anti-cancer agent. It is an effective drug for the treatment of urinary tract infections due to gram negative bacilli.

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