Gramicidin
Gramicidin is active against Gram-positive bacteria, except for the Gram-positive bacilli, and against select Gram-negative organisms, such as Neisseria bacteria. Its therapeutic use is limited to topical application, as it induces hemolysis in lower concentrations than bacteria cell death, so it cannot be administered internally. Since the exterior epidermis is composed of dead cells, applying it to the surface of the skin will not cause harm. It is used primarily as a topical antibiotic and is one of the three constituents of consumer antibiotic polysporin ophthalmic solution. Gramicidin is a group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTHRICIN.
Product Details
Category |
Antibiotics & Antibacterials |
---|---|
Price | POA |
CAS Number | 1405-97-6 |
Formula | C99H140N20O17 |
Molecular Weight | 1882.3 |
Availability | In Stock |
Storage Conditions | Room temperature |
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