Glibenclamide (Glyburide)
Glyburide (Glibenclamide) is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production. Glyburide (Glibenclamide) is an ATP-dependent K+ channel (KIR6, KATP) and CFTR Cl–channel blocker. This compound inhibits recombinant CFTR Cl– channels (IC50 = 20 μM).
Product Details
| Category |
API's & Drug Standards |
|---|---|
| Price | POA |
| CAS Number | 10238-21-8 |
| Formula | C23H28ClN3O5S |
| Molecular Weight | 494.00 |
| Purity | 98.0% |
| Appearance | white to off white powder |
| Availability | In Stock |
| Storage Conditions | +4°C |
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