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DL-Dithiothreitol (DTT)

DL-Dithiothreitol is the common name for a small-molecule redox reagent also known as Cleland’s reagent. An excellent reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides. DTT is effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N′-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol.

Product Details

Category Biochemicals & Diagnostics
Specialities
Price Enquire
CAS Number 3483-12-3
Formula HSCH2CH(OH)CH(OH)CH2SH
Molecular Weight 154.25
Purity 98.0%
Appearance White crystalline powder
Availability Enquire
Storage Conditions +4°C
MSDS Data Sheet Click to download
MDL Number MFCD00004877
Harmonised Tariff 2930909899

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