DL-Amethopterin Hydrate
Amethopterin is a folic acid antagonist and potent anticancer agent. Amethopterin blocks DNA synthesis by preventing the production of tetrahydrofolate cofactors which are required to make thymidine. Amethopterin is actively transported into cells by the folate transporter where it is converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, a dihydrofolate reductase inhibitor.
Product Details
| Category |
API's & Drug Standards Cancer Research and Antivirals |
|---|---|
| Price | POA |
| CAS Number | 60388-53-6 |
| Formula | C20H22N8O5 |
| Molecular Weight | 454.44 |
| Purity | 96.0% |
| Appearance | yellow to orange crystalline powder |
| Availability | In Stock |
| Storage Conditions | -18°C |
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