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5-Aminolevulinic Acid Hydrochloride

5-Aminolevulinic acid Hydrochloride  is the first compound in the porphyrin synthesis pathway, the pathway that leads to heme in mammals and chlorophyll in plants.
In plants, production of δ-ALA is the step on which the speed of synthesis of chlorophyll is regulated. Plants that are fed by external δ-ALA accumulate toxic amounts of chlorophyll precursor, protochlorophyllide, indicating that the synthesis of this intermediate is not suppressed anywhere downwards in the chain of reaction. Protochlorophyllide is a strong photosensitizer in plants.
In Cosmetics,Aminolevulinic acid (ALA) has demonstrated highest efficacy in topical PDT, and has become the most clinically useful. For actinic (solar) keratoses, topical ALA-PDT using Levulan® Kerastick™ (20% topical solution, DUSA Pharmaceuticals) is already postulated to be the treatment of choice. In December 1999, the US FDA approved this topical product for the treatment of actinic keratoses.

Product Details

Category Biochemicals & Diagnostics
Cancer Research and Antivirals
Cosmetic Raw Materials
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CAS Number 5451-09-2
Formula C5H9NO3 · HCl
Molecular Weight 167.59
Purity 98.0%
Appearance crystalline powder
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Storage Conditions -18 °C
MSDS Data Sheet Click to download
MDL Number MFCD00012869
Harmonised Tariff 29225000

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