2-Fluoroadenine-9-β-D-Arabinofuranoside
Fludarabine (the 5′-phosphate) is a prodrug that is converted to F-ara-A, which enters cells and accumulates primarily as the 5′-triphosphate. F-ara-A interferes with DNA synthesis and repair and induces apoptosis of cancer cells. F-ara-A also strongly inhibits DNA methylation, particularly methylation of cytosine in CpG dinucleotide sequences.
Product Details
| Category |
Cancer Research and Antivirals |
|---|---|
| Price | POA |
| CAS Number | 21679-14-1 |
| Formula | C10H12FN5O4 |
| Molecular Weight | 285.23 |
| Purity | 99.0% |
| Appearance | powder white |
| Availability | In Stock |
| Storage Conditions | +4°C |
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