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Fludarabine (the 5′-phosphate) is a prodrug that is converted to F-ara-A, which enters cells and accumulates primarily as the 5′-triphosphate. F-ara-A interferes with DNA synthesis and repair and induces apoptosis of cancer cells. F-ara-A also strongly inhibits DNA methylation, particularly methylation of cytosine in CpG dinucleotide sequences.

Product Details

Category Cancer Research and Antivirals
Price POA
CAS Number 21679-14-1
Formula C10H12FN5O4
Molecular Weight 285.23
Purity 99.0%
Appearance powder white
Availability In Stock
Storage Conditions +4°C

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