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Bestatin Hydrochloride

A metalloprotease inhibitor selective for aminopeptidase. Bestatin is a competitive and specific inhibitor of leucine aminopeptidase, aminopeptidase B, and triamino peptidase. It inhibits aminopeptidase B at 60 nM (using arginine-β-naphthylamide as substrate) and leucine aminopeptidase at 20 nM (leucine-β-naphthylamide as substrate). It showed no inhibition of aminopeptidase A, trypsin, chymotrypsin, elastase, papain, pepsin, or themolysin. It offers promise as a novel analgesic because it protects endogenous opioid peptides against degradation.

Product Details

Category Antibiotics & Antibacterials
Biochemicals & Diagnostics
Price Custom packed. Request price on line.
CAS Number 65391-42-6
Formula  C16H24N2O4 · HCl
Molecular Weight  344.87
Purity Min 98% (on anhydrous basis)
Appearance White to off white powder
Availability In Stock
Storage Conditions -18°C
MDL Number MFCD00058004

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