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Bleomycin Sulphate

Bleomycin is a glycopeptide antitumor antibiotic produced by the bacterium S. verticillus. Its mechanism of action causes single- and double-strand DNA breaks in tumor cells, which interrupts the cell cycle. Bleomycin is thought to achieve this by chelating metal ions, producing a pseudoenzyme that reacts with oxygen to produce superoxide and hydroxide free radicals that cleave DNA. Bleomycin has been used for the treatment of Hodgkin’s lymphoma in combination with doxorubicin, squamous cell carcinomas, testicular cancer, as well as in animal models of pulmonary fibrosis.

Product Details

Category Antibiotics & Antibacterials
Cancer Research and Antivirals
Price POA
CAS Number 9041-93-4
Formula C55H84N17O21S3 • XH2SO4
Molecular Weight 1513.6
Appearance crystalline solid
Purity 95.0%
Storage Conditions -18°C

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